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Biology - Concordia University Libraries Recent Acquisitions

Titles in the call number range QH - QR (Biology) that were added to the Concordia University Libraries collection in the last 60 days.

  • Autophagy : cancer, other pathologies, inflammation, immunity, infection, and aging / edited by M.A. Hayat
    QH 603 L9 A883 2014

    Understanding the importance and necessity of the role of autophagy in health and disease is vital for the studies of cancer, aging, neurodegeneration, immunology, and infectious diseases. Comprehensive and forward thinking, these books offer a valuable guide to both cellular processes while inciting researchers to explore their potentially important connections.

    Considering that autophagy is associated with numerous biological processes, including cellular development and differentiation, cancer (both antitumor and protumor functions), immunity, infectious diseases, inflammation, maintenance of homeostasis, response to cellular stress, and degenerative diseases such as Alzheimer''s, Parkinson''s, Huntington''s, amyotrophic lateral sclerosis, and prion diseases, there is a great need to understanding its role. Cell homeostasis is achieved by balancing biosynthesis and cellular turnover. In spite of the increasing importance of autophagy in various pathophysiological situations (conditions) mentioned above, this process remains underestimated and overlooked. As a consequence, its role in the initiation, stability, maintenance, and progression of these and other diseases (e.g., autoimmune disease) remains poorly understood.

    Volumes in the Series

    Volume 1: Molecular Mechanisms. Elucidates autophagy''s association with numerous biological processes, including cellular development and differentiation, cancer, immunity, infectious diseases, inflammation, maintenance of homeostasis, response to cellular stress, and degenerative diseases such as Alzheimer''s, Parkinson''s, Huntington''s, amyotrophic lateral sclerosis, and prion diseases. Volume 2: Role in General Diseases. Describes the various aspects of the complex process of autophagy in a myriad of devastating human diseases, expanding from a discussion of essential autophagic functions into the role of autophagy in proteins, pathogens, immunity, and general diseases. Volume 3: Role in Specific Diseases. Explores the role of autophagy in specific diseases and developments, including: Crohn''s Disease, Gaucher Disease, Huntington''s Disease, HCV infection, osteoarthritis, and liver injury, with a full section devoted to in-depth exploration of autophagy in tumor development and cancer, as well as the relationship between autophagy and apoptosis. Volume 4: Mitophagy. Presents detailed information on the role of mitophagy, the selective autophagy of mitochondria, in health and disease, by delivering an in-depth treatment of the molecular mechanisms involved in mitophagy initiation and execution, as well as the role of mitophagy in Parkinson Disease, cardiac aging, and skeletal muscle atrophy. Volume 5: Role in Human Diseases. Comprehensively describes the role of autophagy in human diseases, delivering coverage of the antitumor and protumor roles of autophagy; the therapeutic inhibition of autophagy in cancer; and the duality of autophagy''s effects in various cardiovascular, metabolic, and neurodegenerative disorders. Volume 6: Regulation of Autophagy and Selective Autophagy. Provides coverage of the mechanisms of regulation of autophagy; intracellular pathogen use of the autophagy mechanism; the role of autophagy in host immunity; and selective autophagy. Volume 7: Role of Autophagy in Therapeutic Applications. Provides coverage of the latest developments in autophagosome biogenesis and regulation; the role of autophagy in protein quality control; the role of autophagy in apoptosis; autophagy in the cardiovascular system; and the relationships between autophagy and lifestyle. Volume 8: Autophagy and Human Diseases. Reviews recent advancements in the molecular mechanisms underlying a large number of genetic and epigenetic diseases and abnormalities, and introduces new, more effective therapeutic strategies, in the development of targeted drugs and programmed cell death, providing information that will aid on preventing detrimental inflammation. Volume 9: Necrosis and Inflammation in Human Diseases. Emphasizes the role of Autophagy in necrosis and inflammation, explaining in detail the molecular mechanism(s) underlying the formation of autophagosomes, including the progression of Omegasomes to autophagosomes.

  • Antibody therapy : substitution -- immunomodulation -- monoclonal immunotherapy / Paul Imbach, editor

  • Current advances in fern research / Helena Fernández, editor

  • Ecosystem services from forest landscapes : broadscale considerations / edited by Ajith H. Perera, Urmas Peterson, Guillermo Martínez Pastur, Louis R. Iverson

  • Coastal risk assessment : a comprehensive framework for the Bay of Bengal / Ansar Khan, Soumendu Chatterjee

  • Molecular recognition of DNA double helix : gene regulation and photochemistry of BrU substituted DNA ; development of chemical biology tools / Abhijit Saha

  • Numerical ecology with R / Daniel Borcard, François Gillet, Pierre Legendre

  • Computational neuroscience models of the basal ganglia / V. Srinivasa Chakravarthy, Ahmed A. Moustafa

  • Deep Time Analysis A Coherent View of the History of Life / by Mark A.S. McMenamin

  • Antioxidants and antioxidant enzymes in higher plants / Dharmendra K. Gupta, José M. Palma, Francisco J. Corpas, editors
    QK898.A57 A58 2018eb

  • Mathematica for Bioinformatics A Wolfram Language Approach to Omics / by George Mias

  • Concepts in cell biology : history and evolution / Vaidurya Pratap Sahi, František Baluška, editors
    QK725 .C65 2018eb

  • Energy conversion in natural and artificial photosynthesis / Katharina Brinkert

  • Investigation of nanoscopic dynamics and potentials by interferometric scattering microscopy / Jaime Ortega Arroyo

  • Transgenic ascidians / Yasunori Sasakura, editor

  • A clinician's guide to sperm DNA and chromatin damage / Armand Zini, Ashok Agrwal, editors

  • Pot-pollen in stingless bee melittology / Patricia Vit, Silvia R.M. Pedro, David W. Roubik, editors

  • Membrane dynamics and calcium signaling / Joachim Krebs, editor

  • Aeroecology / edited by Phillip B. Chilson, Winifred F. Frick, Jeffrey F. Kelly, Felix Liechti

  • Landscape ecology for sustainable society / Sun-Kee Hong, Nobukazu Nakagoshi, editors

  • Functional surfaces in biology. Stanislav N. Gorb, Elena V. Gorb, editors

  • Tropical dry deciduous forest : research trends and emerging features / J. S. Singh, R.K Chaturvedi

  • Mathematical and theoretical neuroscience : cell, network and data analysis / Giovanni Naldi, Thierry Nieus, editors

  • Bridging the gap between life and physics / Ron Cottam, Willy Ranson

  • Ascorbic acid in plant growth, development and stress tolerance / Mohammas Anwar Hossain, Sergi Munné-Bosch, David J. Burritt, Pedro Diaz-Vivancoa, Masayuki Fujita, Argelia Lorence, editors

  • Heat shock proteins in veterinary medicine and sciences / Alexzander A.A. Asea, Punit Kaur, editors

  • Ticks of Europe and North Africa : A Guide to Species Identification / edited by Agustín Estrada-Peña, Andrei Daniel Mihalca, Trevor N. Petney

  • Animal biometrics : techniques and applications / Santosh Kumar, Sanjay Kumar Singh, Rishav Singh, Amit Kumar Singh

  • Nutritional Antioxidant Therapies: Treatments and Perspectives / edited by Kaïs Hussain Al-Gubory, Ismail Laher

  • Recombinant antibodies for infectious diseases / Theam Soon Lim, editor

  • Cellular automaton modeling of biological pattern formation : characterization, examples, and analysis / Andreas Deutsch, Sabine Dormann ; foreword by Philip K. Maini
    This text explores the use of cellular automata in modeling pattern formation in biological systems.  It describes several mathematical modeling approaches utilizing cellular automata that can be used to study the dynamics of interacting cell systems both in simulation and in practice.  New in this edition are chapters covering cell migration, tissue development, and cancer dynamics, as well as updated references and new research topic suggestions that reflect the rapid development of the field.
    The book begins with an introduction to pattern-forming principles in biology and the various mathematical modeling techniques that can be used to analyze them.  Cellular automaton models are then discussed in detail for different types of cellular processes and interactions, including random movement, cell migration, adhesive cell interaction, alignment and cellular swarming, growth processes, pigment cell pattern formation, tissue development, tumor growth and invasion, and Turing-type patterns and excitable media.  In the final chapter, the authors critically discuss possibilities and limitations of the cellular automaton approach in modeling various biological applications, along with future research directions.  Suggestions for research projects are provided throughout the book to encourage additional engagement with the material, and an accompanying simulator is available for readers to perform their own simulations on several of the models covered in the text.  QR codes are included within the text for easy access to the simulator.
    With its accessible presentation and interdisciplinary approach, Cellular Automaton Modeling of Biological Pattern Formation is suitable for graduate and advanced undergraduate students in mathematical biology, biological modeling, and biological computing.  It will also be a valuable resource for researchers and practitioners in applied mathematics, mathematical biology, computational physics, bioengineering, and computer science.   PRAISE FOR THE FIRST EDITION
    " An ideal guide for someone with a mathematical or physical background to start exploring biological modelling. Importantly, it will also serve as an excellent guide for experienced modellers to innovate and improve their methodologies for analysing simulation results ." --Mathematical Reviews

  • Type IV secretion in gram-negative and gram-positive bacteria / Steffen Backert, Elisabeth Grohmann, editors

  • Hormones, metabolism and the benefits of exercise / Bruce Spiegelman, editor

  • The mammalian auditory pathways : synaptic organization and microcircuits / Douglas L. Oliver, Nell B. Cant, Richard R. Fay, Arthur N. Popper, editors

  • Monarchs in a changing world : biology and conservation of an iconic butterfly / edited by Karen S. Oberhauser, Kelly R. Nail, Sonia Altizer
    QL 561 D3 M6635 2015

    Monarch butterflies are among the most popular insect species in the world and are an icon for conservation groups and environmental education programs. Monarch caterpillars and adults are easily recognizable as welcome visitors to gardens in North America and beyond, and their spectacular migration in eastern North America (from breeding locations in Canada and the United States to overwintering sites in Mexico) has captured the imagination of the public.Monarch migration, behavior, and chemical ecology have been studied for decades. Yet many aspects of monarch biology have come to light in only the past few years. These aspects include questions regarding large-scale trends in monarch population sizes, monarch interactions with pathogens and insect predators, and monarch molecular genetics and large-scale evolution. A growing number of current research findings build on the observations of citizen scientists, who monitor monarch migration, reproduction, survival, and disease. Monarchs face new threats from humans as they navigate a changing landscape marked by deforestation, pesticides, genetically modified crops, and a changing climate, all of which place the future of monarchs and their amazing migration in peril. To meet the demand for a timely synthesis of monarch biology, conservation and outreach, Monarchs in a Changing World summarizes recent developments in scientific research, highlights challenges and responses to threats to monarch conservation, and showcases the many ways that monarchs are used in citizen science programs, outreach, and education. It examines issues pertaining to the eastern and western North American migratory populations, as well as to monarchs in South America, the Pacific and Caribbean Islands, and Europe. The target audience includes entomologists, population biologists, conservation policymakers, and K-12 teachers. Contributors: Anurag A. Agrawal, Cornell University; Jared G. Ali, Michigan State University; Sonia Altizer, University of Georgia; Michael C. Anderson, Eden Prairie, Minnesota; Sophia M. Anderson, Eden Prairie, Minnesota; Kim Bailey, Georgia Department of Natural Resources; Rebecca Batalden, University of Minnesota; Kristen A. Baum, Oklahoma State University; Scott Hoffman Black, Xerces Society for Invertebrate Conservation; Brianna Borders, Xerces Society for Invertebrate Conservation; Lincoln P. Brower, Sweet Briar College; Wendy Caldwell, University of Minnesota; Mariana Cantú-Férnandez, Universidad Nacional Autónoma de México; Nicola Chamberlain, Harvard University; Sonya Charest, Montreal Insectarium; Andrew K. Davis, University of Georgia; Alma De Anda, Covina, California; Guadalupe del Rio Pesado, Alternare, A.C., Mexico; Janet Kudell-Ekstrum, USDA Forest Service; Linda S. Fink, Sweet Briar College; Mark Fishbein, Oklahoma State University; Juan Fernández-Haeger, University of Córdoba, Spain; Eligio García Serrano, Fondo Monarca, Mexico; Mark Garland, Cape May Monarch Monitoring Project; Brian Hayes, Monarch Teacher Network; Elizabeth Howard, Journey North; Mark D. Hunter, University of Michigan; Sarina Jepsen, Xerces Society for Invertebrate Conservation; Diego Jordano, University of Córdoba, Spain; Matthew C. Kaiser, University of Minnesota; Ridlon J. Kiphart, Texas Master Naturalists; Marcus R. Kronforst, University of Chicago; Jim Lovett, University of Kansas; Eric Lee-Mäder, Xerces Society for Invertebrate Conservation; Stephen B. Malcolm, Western Michigan University; Héctor Martínez-Torres, Universidad Nacional Autónoma de México; Susan Meyers, Stone Mountain Memorial Association; Erik A. Mollenhauer, Monarch Teacher Network; Mía Monroe, Xerces Society for Invertebrate Conservation; Eneida B. Montesinos-Patino, Monarch Butterfly Fund; Gail M. Morris, Southwest Monarch Study; Elisha K. Mueller, Oklahoma State University; Kelly R. Nail, University of Minnesota; Karen S. Oberhauser, University of Minnesota; Diego R. Pérez-Salicrup, Universidad Nacional Autónoma de México; Amanda A. Pierce, Emory University; John Pleasants, Iowa State University; Victoria Pocius, University of Kansas; Robert Michael Pyle, Northwest Lepidoptera Survey; M. Isabel Ramírez, Universidad Nacional Autónoma de México; Sergio Rasmann, University of California, Irvine; Gerald Rehfeldt, USDA Forest Service; Eduardo Rendón-Salinas, World Wildlife Fund-Mexico; Leslie Ries, National Socio-Environmental Synthesis Center; Jacobus C. de Roode, Emory University; Richard G. RuBino, Florida State University; Ann Ryan, University of Kansas; Cuauhtémoc Sáenz-Romero, Universidad Michoacana de San Nicolás de Hidalgo; Lidia Salas-Canela, Universidad Nacional Autónoma de México; Phil Schappert, Biophilia Consulting; Priya C. Shahani, Oregon State University; Benjamin H. Slager, Western Michigan University; Michelle J. Solensky, University of Jamestown; Douglas J. Taron, Chicago Academy of Sciences/Peggy Notebaert Nature Museum; Orley R. Taylor, University of Kansas; Rocío Treviño, Protección de la Fauna Mexicana A.C.; Francis X. Villablanca, California Polytechnic State University; Dick Walton, New Jersey Audubon/Cape May Bird Observatory; Ernest H. Williams, Hamilton College; Elisabeth Young-Isebrand, University of Minnesota; Myron P. Zalucki, University of Queensland; Raúl R. Zubieta, Universidad Nacional Autónoma de México

  • Membrane fabrication / edited by Nidal Hilal, Ahmad Fauzi Ismail, Chris J. Wright
    QH 601 M46 2015

    Membranes play a crucial role in ensuring the optimum use and recovery of materials in manufacturing. In the process industries, they are required for efficient production and minimization of environmental impact. They are also essential for the efficient production of clean water, a significant global issue. Membrane Fabrication brings together experts from various disciplines who discuss current membrane fabrication methods and how they are used in the optimization of membrane applications. They present innovative ideas on the development of membrane science and technology with a view toward efficient application of membrane separation processes.

    Exploring fabrication processes for polymeric, inorganic, and composite membranes, the book details the effects of different fabrication conditions and how these conditions can be controlled to optimize membrane construction and the subsequent application of the membrane system. It examines the advantages and disadvantages of each type of membrane, including the malleable yet vulnerable polymeric membranes, the robust yet costly inorganic membranes, and composite membranes, constructed with a blend of inorganic and organic materials.

    Offering a comprehensive survey of a range of fabrication methods, the book is essential reading for those engaged in the R & D activities of the field, as well as those interested in the sustainable development of membranes for various applications. It is also an important resource for industrialists and others charged with developing and introducing membrane processes into production or waste management.

  • Process scale bioseparations for the biopharmaceutical industry / edited by Abhinav A. Shukla, Mark R. Etzel, Shishir Gadam
    QP 551 P693 2007
    The biopharmaceutical industry has become an increasingly important player in the global economy, and the success of these products depends on the development and implementation of cost-effective, robust and scaleable production processes. Bioseparations-also called downstream processing- can be a key source of competitive advantageto biopharmaceutical developers. Process Scale Bioseparations for the Biopharmaceutical Industry brings together scientific principles, empirical approaches, and practical considerations for designing industrial downstream bioprocesses for various classes of biomolecules.

    Using clear language along with numerous case studies, examples, tables, flow charts, and schematics, the book presents perspectives from experienced professionals involved in purification processes and industrial downstream unit operations. The authors provide useful experimental design strategies and guidelines for developing application-specific process scale bioseparations. Chapter topics include harvest by centrifugation and filtration, expanded bed chromatography, protein refolding, modes of preparative chromatography, methodologies for resin screening, membrane chromatography, protein crystallization, viral filtration, ultrafiltration/diafiltration, implementing post-approval downstream process changes for an antibody product, and future trends.

    Ideal for both new and experienced scientists in the biopharmaceutical industry and students, Process Scale Bioseparations for the Biopharmaceutical Industry is a comprehensive resource for all topics relevant to industrial process development.

  • Handbook of cyanobacteria / T.A. Sarma
    QR 99.63 S27 2013

    This handbook acquaints readers with the exciting developments in various areas of cyanobacterial research in the backdrop of the publication of complete genome sequence of the cyanobacterium Synechocystis sp. strain PCC 6803 in 1996. It begins with a summary of the current knowledge on the taxonomy, phylogeny and evolution of cyanobacteria followed by the sequenced genomes, differentiation of akinetes and heterocyst. The book considers mechanisms of cellular movements (gliding, swimming and twitching motions) exhibited by various cyanobacteria in order to adjust to their environmental niches and the operation of the circadian rhythms. It covers cyanobacterial symbiosis, cyanophages and cyanobacterial toxins, followed by a discussion on stress responses (salinity, temperature, desiccation and oxidation).

    A comprehensive account on the developments in all these spheres has been presented in a lucid style with the required background information, molecular techniques employed and models proposed. This handbook constitutes the first such book written by a single author at a level and depth for graduate and research students in botany and microbiology.

  • Advances in technologies for producing food-relevant polyphenols / edited by Jose Cuevas Valenzuela, Jose Rodrigo Vergara-Salinas, and Jose Ricardo Perez-Correa
    QK 898 P764C84 2017

    The growing concern for human wellbeing has generated an increase in the demand for polyphenols, secondary plant metabolites that exhibit different bioactive properties. This increasing demand is mainly due to the current applications in the food industry where polyphenols are considered essential for human health and nutrition.

    Advances in Technologies for Producing Food-relevant Polyphenols provides researchers, scientists, engineers, and professionals involved in the food industry with the latest methodologies and equipment useful to extract, isolate, purify, and analyze polyphenols from different available sources, such as herbs, flora, vegetables, fruits, and agro-industrial wastes. Technologies currently used to add polyphenols to diverse food matrices are also included.

    This book serves a reference to design and scale-up processes to obtain polyphenols from different plant sources and to produce polyphenol-rich foods with bioactive properties (e.g. antioxidant, antibacterial, antiviral, anticancer properties) of interest for human health and wellbeing.

  • Marine glycobiology : principles and applications / edited by Se-Kwon Kim
    QP 702 G577M37 2017

    Marine glycobiology is an emerging and exciting area in the field of science and medicine. Glycobiology, the study of the structure and function of carbohydrates and carbohydrate-containing molecules, is fundamental to all biological systems and represents a developing field of science that has made huge advances in the last half-century. This book revolutionizes the concept of marine glycobiology, focusing on the latest principles and applications of marine glycobiology and their relationships.

  • Computational Chemistry Methodology in Structural Biology and Materials Sciences / Tanmoy Chakraborty
    QP 551 C435 2017

    Computational Chemistry Methodology in Structural Biology and Materials Sciencesprovides a selection of new research in theoretical and experimental chemistry, focusing on topics in the materials science and biological activity.

    Part 1, on Computational Chemistry Methodology in Biological Activity, of the book emphasizes presents new developments in the domain of theoretical and computational chemistry and its applications to bioactive molecules. It looks at various aspects of density functional theory and other issues. Part 2, on Computational Chemistry Methodology in Materials Science, presents informative new research on computational chemistry as applied to materials science.

    The wide range of topics regarding the application of theoretical and experimental chemistry and materials science and biological domain will be valuable in the context of addressing contemporary research problems.

  • Patient specific stem cells / edited by Deepak A. Lamba

  • Cell and matrix mechanics / edited by Roland Kaunas, Texas A&M University, College Station, USA ; Assaf Zemel, Hebrew University of Jerusalem, Israel
    QH 631 C45 3026

    Explores a Range of Multiscale Biomechanics/Mechanobiology Concepts

    Cell and Matrix Mechanicspresents cutting-edge research at the molecular, cellular, and tissue levels in the field of cell mechanics. This book involves key experts in the field, and covers crucial areas of cell and tissue mechanics, with an emphasis on the roles of mechanical forces in cell-matrix interactions. Providing material in each chapter that builds on the previous chapters, it effectively integrates length scales and contains, for each length scale, key experimental observations and corresponding quantitative theoretical models.

    Summarizes the Three Hierarchical Levels of Cell Mechanics

    The book contains 14 chapters and is organized into three sections. The first section focuses on the molecular level, the second section details mechanics at the cellular level, and the third section explores cellular mechanics at the tissue level. The authors offer a thorough description of the roles of mechanical forces in cell and tissue biology, and include specific examples. They incorporate descriptions of associated theoretical models, and provide the data and modeling framework needed for a multi-scale analysis. In addition, they highlight the pioneering studies in cell-matrix mechanics by Albert K. Harris.

    The topics covered include:

    The passive and active mechanical properties of cytoskeletal polymers and associated motor proteins along with the behavior of polymer networks The mechanical properties of the cell membrane, with an emphasis on membrane protein activation caused by membrane forces The hierarchical organization of collagen fibrils, revealing that a delicate balance exists between specific and nonspecific interactions to result in a structure with semicrystalline order as well as loose associations The roles of matrix mechanical properties on cell adhesion and function along with different mechanical mechanisms of cell-cell interactions The effects of mechanical loading on cell cytoskeletal remodeling, summarizing various modeling approaches that explain possible mechanisms regulating the alignment of actin stress fibers in response to stretching The mechanical testing of cell-populated collagen matrices, along with theory relating the passive and active mechanical properties of the engineered tissues Cell migration behavior in 3-D matrices and in collective cell motility The role of mechanics in cartilage development The roles of both cellular and external forces on tissue morphogenesis The roles of mechanical forces on tumor growth and cancer metastasis

    Cell and Matrix Mechanicssuccinctly and systematically explains the roles of mechanical forces in cell-matrix biology. Practitioners and researchers in engineering and physics, as well as graduate students in biomedical engineering and mechanical engineering related to mechanobiology, can benefit from this work.

  • Applied molecular biotechnology : the next generation of genetic engineering / edited by Muhammad Sarwar Khan, Iqrar Ahmad Khan, Debmalya Barh
    QH 442 A67 2016

    Applied Molecular Biotechnology: The Next Generation of Genetic Engineeringexplains state-of-the-art advances in the rapidly developing area of molecular biotechnology, the technology of the new millennium. Comprised of chapters authored by leading experts in their respective fields, this authoritative reference text:

    Highlights the latest omics-based tools and approaches used in modern biotechnology Explains how various molecular biology technologies can be used to develop transgenic plants and how those plants can meet growing food and plant-derived product demands Discusses chloroplast gene expression systems, mitochondrial omics, plant functional genomics, and whole-genome resequencing for crop improvement Explores plant-microbe and plant-insect interactions affecting plant protection and productivity Covers animal models, pharmacogenomics, human tissue banking, and the molecular diagnosis of diseases such as cervical cancer, obesity, and diabetes Examines the molecular aspects of viral diseases, production of industrial commodities using viral biotechnology, and biotechnological uses of magnetic nanoparticles Describes the use of biotechnology in the food, chemical, pharmaceutical, environmental conservation, and renewable energy sectors

    Applied Molecular Biotechnology: The Next Generation of Genetic Engineeringserves as a springboard for new discoveries in molecular biology and its applications. Thus, this book is an invaluable resource for students and researchers of molecular biotechnology.

  • Chemistry of peptide synthesis / N. Leo Benoiton
    QP 552 P4B46 2006
    Chemistry of Peptide Synthesis is a complete overview of how peptides are synthesized and what techniques are likely to generate the most desirable reactions. Incorporating elements from the author's role of Career Investigator of the Medical Research Council of Canada and his extensive teaching career, the book emphasizes learning rather than memorization. The text uses clear language and schematics to present concepts progressively, carefully excluding unnecessary details and providing a historical context in which to appreciate the development of the field.

    The author first outlines the fundamentals of peptide synthesis, focusing on the intermediates in aminolysis reactions. Gradually the text builds into discussions of the applicability of coupling reactions, stereomutation, methods of deprotection, solid-phase synthesis, side-chain protection and side reactions, and amplification on coupling methods. The book clarifies the differences between oxazolones from amino-acid derivatives and segments and the implications of their formation on the chiral integrity of products. The author offers a critical analysis of the mechanisms of coupling reactions and the desirability of preactivation. The text explains hindrance and the nucleophilicity of tertiary amines and rationalizes their use. The book also explores mechanisms of acidolysis and the dual role of nucleophiles as reactants and scavengers.

    Chemistry of Peptide Synthesis supplies a broad, yet straightforward approach that appeals to those with limited knowledge of organic chemistry or chemists from other fields as well as in-depth coverage that can be appreciated by experienced peptidologists.

  • Adsorption on mesoporous metal-organic frameworks in solution for clean energy, environment and healthcare / by Alexander Samokhvalov
    QH 545 M45S266 2017

    Adsorption and desorption in solution play significant roles in separations, detoxification of waste streams, in purification, chromatography, heterogeneous catalysis, metabolism of medicinal drugs, and beyond. Metal-Organic Frameworks (MOFs) are well-ordered 3-dimensional hybrid organic-inorganic polymers which contain metal cations and the structure-building organic "linker" units. Mesoporous MOFs with pore sizes 2-50 nm are particularly suitable for adsorption and adsorption-based separations of large molecules of organic and bio-organic compounds.

    Thousands of organic compounds and, in particular, aromatic and heterocyclic compounds are widely used as feedstock for industrial chemical synthesis, as fine chemicals, major components of liquid fossil fuels, dyestuffs, industrial solvents, agricultural chemicals, medicinal drugs, pharmaceuticals and personal care products (PPCPs), and active pharmaceutical ingredients (APIs). There is a strong interest towards synthesis, characterization and studies of both known and newly synthesized mesoporous MOFs for adsorption in solution to achieve the high adsorption capacity, selectivity, and the possibility of multiple regeneration of "spent" sorbent.

    This book covers experimental fundamental research on using mesoporous MOFs in emerging applications of major industrial, environmental and academic importance, especially purification of water and liquid fossil fuels and in advanced biomedical technologies.

  • Modern Industrial Microbiology and Biotechnology, Second Edition / Nduka Okafor
    QR 53 O334 2017

    The field of industrial microbiology involves a thorough knowledge of the microbial physiology behind the processes in the large-scale, profit-oriented production of microbe-related goods which are the subject of the field. In recent times a paradigm shift has occurred, and a molecular understanding of the various processes by which plants, animals and microorganisms are manipulated is now central to industrial microbiology. Thus the various applications of industrial microbiology are covered broadly, with emphasis on the physiological and genomic principles behind these applications. Relevance of the new elements such as bioinformatics, genomics, proteomics, site-directed mutation and metabolic engineering, which have necessitated the paradigm shift in industrial microbiology are discussed.

  • Stem cell engineering : principles and practices / edited by David Schaffer, Joseph D. Bronzino, Donald R. Peterson
    QH 588 S83S74 2013

    While the potential of stem cells is recognized, their proliferation and differentiation must be more precisely controlled to maximize the production of therapeutically relevant cells and for cell replacement therapies to minimize contamination with residual cells that can give rise to side effects. How can engineers make contributions to address these challenges? With contributions from pioneers and experts, Stem Cell Engineering: Principles and Practices highlights recent advances in the understanding of the cellular and molecular composition of the stem cell niche, as well as approaches to build upon this basic information to direct stem cell differentiation into therapeutically valuable lineages.

    The growing recognition of stem cells as an important and exciting field will continue to draw investigators with diverse backgrounds--from biology, engineering, and the physical sciences--and thereby enable further progress in these and other new directions. This book discusses advances made during the last decade that have led to increasingly defined culture systems for growing stem cells, starting from co-culture with feeder cells in the presence of serum to growth on synthetic substrates in defined medium. In addition to highlighting many recent advances, it underscores the need for future work.

  • Synthetic biology handbook / Darren N. Nesbeth, University College London, UK
    QH 438.7 N47 2016

    TheSynthetic Biology Handbookexplains the major goals of the field of synthetic biology and presents the technical details of the latest advances made in achieving those goals. Offering a comprehensive overview of the current areas of focus in synthetic biology, this handbook:

    Explores the standardisation of classic molecular bioscience approaches Addresses the societal context and potential impacts of synthetic biology Discusses the use of legacy systems as tools for new product development Examines the design and construction of de novo cells and genetic codes Describes computational methods for designing genes and gene networks

    Thus, theSynthetic Biology Handbookprovides an accurate sense of the scope of synthetic biology today. The handbook also affords readers with an opportunity to scrutinize the underlying science and decide for themselves what aspects of synthetic biology are most valuable to their research and practice.

  • Supercritical fluids technology in lipase catalyzed processes / Sulaiman Al-Zuhair and Hanifa Taher
    QP 609 L5A49 2016

    The book focuses on supercritical fluids as a green alternative reaction medium in catalytic reactions involving lipases. Lipases have great potential in industrial applications and the book describes their main sources, reaction kinetics, structure, physicochemical characteristics, and applications. Techniques of isolating, extracting and purifying are given as are lipase immobilization and its advantages over soluble lipases, immobilization techniques, immobilization materials, and bioreactor configurations using immobilized lipase. The advantages of non-aqueous media in biochemical synthesis are discussed. The book includes a case study on using SC-CO2 for biodiesel production

  • The microflow cytometer / Frances S. Ligler, Jason S. Kim
    QH 585.5 F56L54 2010

    The field of microfluidic flow cytometry is growing at a fast rate. This volume describes the development of inexpensive, portable flow cytometers through incorporation of microfluidic technologies and small optical components. The book discusses the underlying microfluidic theories essential for microflow cytometry, as well as advances that are representative of the current state-of-the-art. Numerous research groups leading the field are currently presenting design and fabrication strategies for these innovative component technologies, and the book reviews integration of the components into functional prototype devices for analysis and manipulation of particles and cells. It also examines multiple currently available commercial systems to highlight both strengths and areas for improvement.

  • Omics : biomedical perspectives and applications / edited by Debmalya Barh, Kenneth Blum, Margaret Anne Madigan
    QH 324.2 O45 2012

    A reflection of the explosion of research and development in this field, OMICS: Biomedical Perspectives and Applicationsexplores applications of omics in bioinformatics, cancer research and therapy, diabetes research, plant science, molecular biology, and neurosciences. A select editorial panel of experts discusses their cutting edge omics research and novel technologies, supplying a basic platform of methods and applications and a resource for enhanced cross-pollination in a multiomics approach to future endeavors in the fertile fields of omics research.

    After an introduction on the omics universe, the book presents modern omics and its applications in nanotechnology, genomics, proteomics, metagenomics, toxicogenomics, immunomics, nutrigenomics, diabetes, neurology, cardiology, and cancer to name just a few. The book begins with an overview of omics and omic technologies such as cellomics, glycomics, and lipidomics. It also discusses bioinformatics, demonstrating how it can be a tool in omics, and examines the various approaches of omics technology in toxicology research and applications in biomedical sciences.

    While there are a long list of omics books available, most focus narrowly on one area. Presenting a wide view of the current status of integrative omics, this resource contains complete coverage of omics in research and therapy, ranging from neuroscience to cardiology. It collates recent developments in the field into a state-of-the-art framework for this discipline.

  • Transport phenomena in biomedical engineering : principles and practices / edited by Robert A. Peattie ... [et al.]
    QH 509 T73 2013

    Design, analysis and simulation of tissue constructs is an integral part of the ever-evolving field of biomedical engineering. The study of reaction kinetics, particularly when coupled with complex physical phenomena such as the transport of heat, mass and momentum, is required to determine or predict performance of biologically-based systems whether for research or clinical implementation. Transport Phenomena in Biomedical Engineering: Principles and Practices explores the concepts of transport phenomena alongside chemical reaction kinetics and thermodynamics to introduce the field of reaction engineering as it applies to physiologic systems in health and disease. It emphasizes the role played by these fundamental physical processes.

    The book first examines elementary concepts such as control volume selection and flow systems. It provides a comprehensive treatment with an overview of major research topics related to transport phenomena pertaining to biomedical engineering. Although each chapter is self-contained, they all bring forth and reinforce similar concepts through applications and discussions. With contributions from world-class experts, the book unmasks the fundamental phenomenological events in engineering devices and explores how to use them to meet the objectives of specific applications. It includes coverage of applications to drug delivery and cell- and tissue-based therapies.

  • Handbook of online and near-real-time methods in microbiology / editors, Maximilian Lackner, Institute of Advanced Engineering Technologies, University of Applied Sciences FH Technikum Wien, Vienna, Austria, Philipp Stadler, TU Wien, Centre for
    QR 72.5 H36 2017

    Rapid detection and indication of the microbiological quality of liquids is an emerging topic that has high potential for numerous applications in the fields of environmental monitoring, industrial process control and medical surveillance. Latest technologies allow online and near-real-time quantitative or qualitative microbial measurements with a significantly higher temporal resolution than traditional methods. Such novel developments will significantly enhance quality monitoring of water resources and liquids and have great capability for automation, control and optimization of industrial processes. Therefore, such methods are assumed to have major impacts on scientific research and technical applications in the near future.

    The book presents cutting edge research on frontiers in microbiological detection from leading experts: Seven chapters containing review articles on emerging and state-of-the-art online and near-real-time methods of microorganism detection and - indication are giving a comprehensive insight into this novel field. A balance between chapters from industry and contributions from academia was aimed for, covering the broad field of microbiological quality of waters and liquids in environmental, industrial and medical systems. This handbook also contains an extensive glossary pointing out and describing relevant terms and definitions.

    This handbook is the first of its kind and is a timely, comprehensive source of information for researchers and engineers in the areas of biotechnology, environmental sciences, control technology and the process industries.

  • Isolation and purification of proteins / edited by Rajni Hatti-Kaul, Bo Mattiasson
    QP 551 I865 2003
    This publication details the isolation of proteins from biological materials, techniques for solid-liquid separation, concentration, crystallization, chromatography, scale-up, process monitoring, product formulation, and regulatory and commercial considerations in protein production. The authors discuss the release of protein from a biological host, selectivity in affinity chromatography, precipitation of proteins (both non-specific and specific), extraction for rapid protein isolation, adsorption as an initial step for the capture of proteins, scale-up and commercial production of recombinant proteins, and process monitoring in downstream processing.

  • Chemistry and technology of plant substances : chemical and biochemical aspects / edited by Alexandr V. Kutchin, D. Sc., Lyudmila N. Shishkina, D. Sc., Larissa I. Weisfeld, Ph. D
    QK 861 C44 2018

    Chemistry and Technology of Plant Substances: Chemical and Biochemical Aspectsdemonstrates the progress and promise of developing new chemical substances from renewable sources of chemical raw materials. The volume brings together new achievements in the field of research and processing of plant raw materials and the synthesis of natural compounds for the production of biologically active substances and drugs. The volume looks closely at the rational use of renewable raw materials, which is the source of new compounds and intermediates for the chemical industry. It covers a wide range of problems associated with the use of the components of plants to produce new substances with a wide variety of purposes.

    According to the latest estimates, plants form about a million chemical substances. In some cases, plant products have pharmacological or biological activity that can be of therapeutic benefit in treating diseases. In addition, due to the structural diversity of plant material, chemical synthesis is easily reachable. Synthetic analogs of natural products with improved potency and safety can be prepared by chemical synthesis. Such synthetic analogs are safer for humans. Plant materials are often used as starting points for drug discovery. Chemistry and Technology of Plant Substances: Chemical and Biochemical Aspects presents the theoretical trends and recent practical achievements on complex processing of plant-based raw materials. Low molecular weight components, isolated from plant material, are widely used in fine organic synthesis. High molecular weight polysaccharides of conifers and other greens, such as pectin and hemicellulose, are the basis for the creation of anticoagulants and other drugs. The range of research papers presented in the book is quite wide: from fundamental and applied problems of wood chemistry and organic synthesis to biological activity of natural compounds.

    The book provides valuable information for those skilled in organic chemistry, chemical engineers, researchers and scientists as well as for faculty and upper-level students.

    This volume, Chemistry and Technology of Plant Substances: Chemical and Biochemical Aspects , was created on the initiative of Emanuel Institute of Biochemical Physics of the Russian Academy of Sciences (Moscow) and the Institute of Chemistry of Komi Scientific Center of Ural Branch of the Russian Academy of Sciences (Syktyvkar).

  • The epochs of nature / Georges-Louis Leclerc, le comte de Buffon ; translated and edited by Jan Zalasiewicz, Anne-Sophie Milon, and Mateusz Zalasiewicz ; introduction by Jan Zalasiewicz, Sverker Sörlin, Libby Robin, and Jacques Grinevald ; illustrations by Anne-Sophie Milon
    QH 45 B913 2018
    Georges-Louis Leclerc, le comte de Buffon's The Epochs of Nature , originally published as Les Époques de la Nature in 1778, is one of the first great popular science books, a work of style and insight that was devoured by Catherine the Great of Russia and influenced Humboldt, Darwin, Lyell, Vernadsky, and many other renowned scientists. It is the first geological history of the world, stretching from the Earth's origins to its foreseen end, and though Buffon was limited by the scientific knowledge of his era--the substance of the Earth was not, as he asserts, dragged out of the sun by a giant comet, nor is the sun's heat generated by tidal forces--many of his deductions appear today as startling insights. And yet, The Epochs of Nature has never before been available in its entirety in English--until now.

    In seven epochs, Buffon reveals the main features of an evolving Earth, from its hard rock substrate to the sedimentary layers on top, from the minerals and fossils found within these layers to volcanoes, earthquakes, and rises and falls in sea level--and he even touches on age-old mysteries like why the sun shines. In one of many moments of striking scientific prescience, Buffon details evidence for species extinction a generation before Cuvier's more famous assertion of the phenomenon. His seventh and final epoch does nothing less than offer the first geological glimpse of the idea that humans are altering the very foundations of the Earth--an idea of remarkable resonance as we debate the designation of another epoch: the Anthropocene. Also featuring Buffon's extensive "Notes Justificatives," in which he offers further evidence to support his assertions (and discusses vanished monstrous North American beasts--what we know as mastodons--as well as the potential existence of human giants), plus an enlightening introduction by editor and translator Jan Zalasiewicz and historians of science Sverker Sörlin, Libby Robin, and Jacques Grinevald, this extraordinary new translation revives Buffon's quite literally groundbreaking work for a new age.

  • Systematic : how systems biology is transforming modern medicine / James R. Valcourt
    QH 324.2 V346 2017

    A brilliant young scientist introduces us to the fascinating field that is changing our understanding of how the body works and the way we can approach healing.

    SYSTEMATIC is the first book to introduce general readers to systems biology, which is improving medical treatments and our understanding of living things. In traditional bottom-up biology, a biologist might spend years studying how a single protein works, but systems biology studies how networks of those proteins work together--how they promote health and how to remedy the situation when the system isn't functioning properly.

    Breakthroughs in systems biology became possible only when powerful computer technology enabled researchers to process massive amounts of data to study complete systems, and has led to progress in the study of gene regulation and inheritance, cancer drugs personalized to an individual's genetically unique tumor, insights into how the brain works, and the discovery that the bacteria and other microbes that live in the gut may drive malnutrition and obesity. Systems biology is allowing us to understand more complex phenomena than ever before.

    In accessible prose, SYSTEMATIC sheds light not only on how systems within the body work, but also on how research is yielding new kinds of remedies that enhance and harness the body's own defenses.

  • The Subjugation of Canadian Wildlife : Failures of Principle and Policy / Max Foran
    QL 84.24 F57 2018
    Hardly a day goes by without news of the extinction or endangerment of yet another animal species, followed by urgent but largely unheeded calls for action. An eloquent denunciation of the failures of Canada's government and society to protect wildlife from human exploitation, Max Foran's The Subjugation of Canadian Wildlife argues that a root cause of wildlife depletions and habitat loss is the culturally ingrained beliefs that underpin management practices and policies. Tracing the evolution of the highly contestable assumptions that define the human-wildlife relationship, Foran stresses the price wild animals pay for human self-interest. Using several examples of government oversight at the federal, provincial, and territorial levels, from the Species at Risk Act to the Biodiversity Strategy, Protected Areas Network, and provincial management plans, this volume shows that wildlife policies are as much - or more - about human needs, priorities, and profit as they are about preservation. Challenging established concepts including ecological integrity, adaptive management, sport hunting as conservation, and the flawed belief that wildlife is a renewable resource, the author compels us to recognize animals as sentient individuals and as integral components of complex ecological systems. A passionate critique of contemporary wildlife policy, The Subjugation of Canadian Wildlife calls for belief-change as the best hope for an ecologically healthy, wildlife-rich Canada.

  • Good quality : the routinization of sperm banking in China / Ayo Wahlberg
    QP 255 W28 2018
    From its crude and uneasy beginnings thirty years ago, Chinese sperm banking has become a routine part of China's pervasive and restrictive reproductive complex. Today, there are sperm banks in each of China's twenty-two provinces, the biggest of which screen some three thousand to four thousand potential donors each year. Given the estimated one to two million azoospermic men--those who are unable to produce their own sperm--the demand remains insatiable. China's twenty-two sperm banks cannot keep up, spurring sperm bank directors to publicly lament chronic shortages and even warn of a national 'sperm crisis' ( jingzi weiji ).

    Good Quality explores the issues behind the crisis, including declining sperm quality in the country due to environmental pollution, as well as a chronic national shortage of donors. In doing so, Wahlberg outlines the specific style of Chinese sperm banking that has emerged, shaped by the particular cultural, juridical, economic and social configurations that make up China's restrictive reproductive complex. Good Quality shows how this high-throughput style shapes the ways in which men experience donation and how sperm is made available to couples who can afford it.

  • Fundamentals of microbiome science : how microbes shape animal biology / Angela E. Douglas
    QR 1 D68 2018

    An essential introduction to microbiome science, a new cutting-edge discipline that is transforming the life sciences

    This book provides an accessible and authoritative guide to the fundamental principles of microbiome science, an exciting and fast-emerging new discipline that is reshaping many aspects of the life sciences. Resident microbes in healthy animals--including humans--can dictate many traits of the animal host. This animal microbiome is a second immune system conferring protection against pathogens; it can structure host metabolism in animals as diverse as reef corals and hibernating mammals; and it may influence animal behavior, from social recognition to emotional states. These microbial partners can also drive ecologically important traits, from thermal tolerance to diet, and have contributed to animal diversification over long evolutionary timescales.

    Drawing on concepts and data across a broad range of disciplines and systems, Angela Douglas provides a conceptual framework for understanding these animal-microbe interactions while shedding critical light on the scientific challenges that lie ahead. Douglas explains why microbiome science demands creative and interdisciplinary thinking--the capacity to combine microbiology with animal physiology, ecological theory with immunology, and evolutionary perspectives with metabolic science.

    An essential introduction to a cutting-edge field that is revolutionizing the life sciences, this book explains why microbiome science presents a more complete picture of the biology of humans and other animals, and how it can deliver novel therapies for many medical conditions and new strategies for pest control.

  • Animal spaces, beastly places : new geographies of human-animal relations / edited by Chris Philo and Chris Wilbert
    QL 85 A52 2000
    Animal Spaces, Beastly Places examines how animals interact and relate with people in different ways. Using a comprehensive range of examples, which include feral cats and wild wolves, to domestic animals and intensively farmed cattle, the contributors explore the complex relations in which humans and non-human animals are mixed together. Our emotions involving animals range from those of love and compassion to untold cruelty, force, violence and power. As humans we have placed different animals into different categories, according to some notion of species, usefulness, domesticity or wildness. As a result of these varying and often contested orderings, animals are assigned to particular places and spaces. Animal Spaces, Beastly Places shows us that there are many exceptions and variations on the spatiality of human-animal spatial orderings, within and across cultures, and over time. It develops new ways of thinking about human animal interactions and encourages us to find better ways for humans and animals to live together.

  • Model behavior : animal experiments, complexity, and the genetics of psychiatric disorders / Nicole C. Nelson
    QH 457 N45 2018
    Mice are used as model organisms across a wide range of fields in science today--but it is far from obvious how studying a mouse in a maze can help us understand human problems like alcoholism or anxiety. How do scientists convince funders, fellow scientists, the general public, and even themselves that animal experiments are a good way of producing knowledge about the genetics of human behavior? In Model Behavior , Nicole C. Nelson takes us inside an animal behavior genetics laboratory to examine how scientists create and manage the foundational knowledge of their field.

    Behavior genetics is a particularly challenging field for making a clear-cut case that mouse experiments work, because researchers believe that both the phenomena they are studying and the animal models they are using are complex. These assumptions of complexity change the nature of what laboratory work produces. Whereas historical and ethnographic studies traditionally portray the laboratory as a place where scientists control, simplify, and stabilize nature in the service of producing durable facts, the laboratory that emerges from Nelson's extensive interviews and fieldwork is a place where stable findings are always just out of reach. The ongoing work of managing precarious experimental systems means that researchers learn as much--if not more--about the impact of the environment on behavior as they do about genetics. Model Behavior offers a compelling portrait of life in a twenty-first-century laboratory, where partial, provisional answers to complex scientific questions are increasingly the norm.

  • Moral entanglements : conserving birds in Britain and Germany / Stefan Bargheer
    QL 676.5 B255 2018
    At the center of Stefan Bargheer's account of bird watching, field ornithology, and nature conservation in Britain and Germany stands the question of how values change over time and how individuals develop moral commitments. Using life history data derived from written narratives and oral histories, Moral Entanglements follows the development of conservation from the point in time at which the greatest declines in bird life took place to the current efforts in large-scale biodiversity conservation and environmental policy within the European Union. While often depicted as the outcome of an environmental revolution that has taken place since the 1960s, Bargheer demonstrates to the contrary that the relevant practices and institutions that shape contemporary conservation have evolved gradually since the early nineteenth century. Moral Entanglements further shows that the practices and institutions in which bird conservation is entangled differ between the two countries. In Britain, birds derived their meaning in the context of the game of bird watching as a leisure activity. Here birds are now, as then, the most popular and best protected taxonomic group of wildlife due to their particularly suitable status as toys in a collecting game, turning nature into a playground. In Germany, by contrast, birds were initially part of the world of work. They were protected as useful economic tools, rendering services of ecological pest control in a system of agricultural production modeled after the factory shop floor. Based on this extensive analysis, Bargheer formulates a sociology of morality informed by a pragmatist theory of value.

  • Darwin's evolving identity : adventure, ambition, and the sin of speculation / Alistair Sponsel
    QH 31 D2 S66 2018
    Why--against his mentor's exhortations to publish--did Charles Darwin take twenty years to reveal his theory of evolution by natural selection? In Darwin's Evolving Identity , Alistair Sponsel argues that Darwin adopted this cautious approach to atone for his provocative theorizing as a young author spurred by that mentor, the geologist Charles Lyell. While we might expect him to have been tormented by guilt about his private study of evolution, Darwin was most distressed by harsh reactions to his published work on coral reefs, volcanoes, and earthquakes, judging himself guilty of an authorial "sin of speculation." It was the battle to defend himself against charges of overzealous theorizing as a geologist, rather than the prospect of broader public outcry over evolution, which made Darwin such a cautious author of Origin of Species .

    Drawing on his own ambitious research in Darwin's manuscripts and at the Beagle 's remotest ports of call, Sponsel takes us from the ocean to the Origin and beyond. He provides a vivid new picture of Darwin's career as a voyaging naturalist and metropolitan author, and in doing so makes a bold argument about how we should understand the history of scientific theories.

  • Bombs away : militarization, conservation, and ecological restoration / David G. Havlick
    QH 541.15 R45 H38 2018
    When viewed from space, the Korean Peninsula is crossed by a thin green ribbon. On the ground, its mix of dense vegetation and cleared borderlands serves as home to dozens of species that are extinct or endangered elsewhere on the peninsula. This is Korea's demilitarized zone--one of the most dangerous places on earth for humans, and paradoxically one of the safest for wildlife. Although this zone was not intentionally created for conservation, across the globe hundreds of millions of acres of former military zones and bases are being converted to restoration areas, refuges, and conservation lands. David G. Havlick has traveled the world visiting these spaces of military-to-wildlife transition, and in Bombs Away he explores both the challenges--physical, historical, and cultural--and fascinating ecological possibilities of military site conversions.

    Looking at particular international sites of transition--from Indiana's Big Oaks National Wildlife Refuge to Cold War remnants along the former Iron Curtain--Havlick argues that these new frontiers of conservation must accomplish seemingly antithetical aims: rebuilding and protecting ecosystems, or restoring life, while also commemorating the historical and cultural legacies of warfare and militarization. Developing these ideas further, he shows that despite the ecological devastation often wrought by military testing and training, these activities need not be inconsistent with environmental goals, and in some cases can even complement them--a concept he calls ecological militarization. A profound, clear explication of landscapes both fraught and fecund, marked by death but also reservoirs of life, Bombs Away shows us how "military activities, conservation goals, and ecological restoration efforts are made to work together to create new kinds of places and new conceptions of place."

  • Plants that kill : a natural history of the world's most poisonous plants / Elizabeth A. Dauncey and Sonny Larsson
    QK 100 A1 D38 2018

    A full-color illustrated guide to the natural history of the most poisonous plants on earth

    This richly illustrated book provides an in-depth natural history of the most poisonous plants on earth, covering everything from the lethal effects of hemlock and deadly nightshade to the uses of such plants in medicine, ritual, and chemical warfare.

    Featuring hundreds of color photos and diagrams throughout, Plants That Kill explains how certain plants evolved toxicity to deter herbivores and other threats and sheds light on their physiology and the biochemistry involved in the production of their toxins. It discusses the interactions of poisonous plants with other organisms--particularly humans--and explores the various ways plant toxins can target the normal functioning of bodily systems in mammals, from the effects of wolfsbane on the heart to toxins that cause a skin reaction when combined with the sun's rays. This intriguing book also looks at plants that can harm you only if your exposure to them is prolonged, the ethnobotany of poisons throughout human history, and much more.

    A must for experts and armchair botanists alike, Plants That Kill is the essential illustrated compendium to these deadly and intriguing plants.

    Provides an authoritative natural history of the most poisonous plants on earth Features hundreds of color illustrations throughout Looks at how and why plants produce toxins Describes the effects of numerous poisonous plants, from hemlock and deadly nightshade to poppies and tobacco Explains poisonous plants' evolution, survival strategies, physiology, and biochemistry Discusses the uses of poisonous plants in medicine, rituals, warfare, and more

  • The immune system : a very short introduction / Paul Klenerman
    QR 181.7 K54 2017
    The immune system is central to human health and the focus of much medical research. Growing understanding of the immune system, and especially the creation of immune memory (long lasting protection), which can be harnessed in the design of vaccines, have been major breakthroughs in medicine.In this Very Short Introduction, Paul Klenerman describes the immune system, and how it works in health and disease. In particular he focuses on the human immune system, considering how it evolved, the basic rules that govern its behaviour, and the major health threats where it is important. Theimmune system comprises a series of organs, cells and chemical messengers which work together as a team to provide defence against infection. Klenerman discusses these components, the critical signals that trigger them and how they exert their protective effects, including so-called "innate" immuneresponses, which react very fast to infection, and "adaptive" immune responses, which have huge diversity and a capacity to recognise and defend against a massive array of micro-organisms. Klenerman also considers what happens when our immune systems fail to be activated effectively, leading toserious infections, problems with inherited diseases, and also HIV/AIDS. At the opposite extreme, as Klenerman shows, an over-exaggerated immune response leads to inflammatory diseases such as Multiple Sclerosis and Rheumatoid Arthritis, as well as allergy and asthma. Finally he looks at the "Immunesystem v2.o" - how immune therapies and vaccines can be advanced to protect us against the major diseases of the 21st century.ABOUT THE SERIES: The Very Short Introductions series from Oxford University Press contains hundreds of titles in almost every subject area. These pocket-sized books are the perfect way to get ahead in a new subject quickly. Our expert authors combine facts, analysis, perspective, new ideas, andenthusiasm to make interesting and challenging topics highly readable.

  • Seeds of the earth : the Vavilov Institute / Mario Del Curto
    QK 981.7 D45 2017

    In a former tsarist palace in what is now St. Petersburg, botanist Nikola Vavilov (1887-1943), predicting the disappearance of plant biodiversity, built the world's first seed bank. A living museum, the Vavilov Institute hosts roughly 330,000 specimens and stands as a monument to its creator--a scientist who devoted his life to food security and died of starvation, a political scapegoat in the basement of a Soviet prison. One hundred years after Vavilov's first specimen-collecting expedition, Swiss photographer Mario Del Curto (born 1955) retraces the botanist's steps and meets the people who continue his work, seeking, selecting and preserving the planet's plant species. Part meditation on the scope of Vavilov's work and part travelogue into the heart of the Vavilov Institute and its 12 satellite stations, Seeds of the Earth is a beautiful and urgent meditation on food security, ecology and history.

  • Inspiring science : Jim Watson and the age of DNA / edited by John R. Inglis, Joseph Sambrook, Jan A. Witkowski ; with a foreword by Matt Ridley
    QH 506 W4 I55 2003
    For James D. Watson, the year 2003 was momentous: The 50th anniversary of the discovery, with Francis Crick, of the DNA double helix; the 35th anniversary of the publication of his bestselling memoir of the discovery, The Double Helix; the 35th anniversary of his appointment as Director of Cold Spring Harbor Laboratory, an institution he molded into a research and education center of international renown and prestige: and the year in which the sequencing of the human genome was completed, a project of unprecedented international effort and coordination that Watson got off the ground and sustained during its first, critical years. In the course of his 75 years, Watson has achieved a reputation as outspoken, capricious, abrasive, and ruthless in pursuing his visionary goals. Few other scientists have achieved his celebrity status, or enjoyed it so much, without losing professional credibility. Yet behind the public notoriety there is a complexity apparent only to those who know Watson as a colleague, mentor, inspiration, and friend. This book gives voice to 43 of these individualspeople of distinction who have worked with Watson as a scientist, educator, author, administrator, and government official. Their essays cover much of his scientific life and, taken together, create a portrait of a complex man whose originality and force of will have produced extraordinary achievements.

  • PCR technology : principles and applications for DNA amplification / Henry A. Erlich, editor
    QP 606 D46 P37 1991
    Polymerase chain reaction (PCR) technology is a revolutionary innovation which enables scientists to rapidly generate large amounts of genetic material from a slight trace which would otherwise be too small to analyze. With applications in both research and diagnostics, PCR is becoming astandard procedure in biotechnology and medical diagnostic laboratories. This book is an introduction and guide to the new technology, covering the basic methodologies and their applications in research and medicine, emphasizing practical aspects. Each chapter is written by pioneers in the fieldand most include detailed protocols and favorite PCR "recipes". Students and researchers in all areas of biotechnology and molecular biology will find this book the introduction to PCR they've been looking for.

  • The formation of vegetable mould, through the action of worms, with observations on their habits. / By Charles Darwin, LL. D., F.R.S
    QL 394 D37 F67 1883

  • Mitochondria, a practical approach / edited by V.M. Darley-Usmar, D. Rickwood, M.T. Wilson
    QH 603 M5M536 1987
    Mitochondriais a unique and comprehensive guide to the key techniques used in both enzymology and molecular biology studies. Some of the protocols described in this book are well-established but, until now, have been scattered amongst enzymology manuals and biochemistry research journals. Other techniques are described in detail for the first time.

  • PCR technology : principles and applications for DNA amplification / Henry A. Erlich, editor
    QP 606 D46 P37 1989
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